Dermal fillers are injectable agents of new generation, which are applied for the correction of the cheekbones, chin, nose and facial contours, lifting eyelids and improve the overall skin hydro-balance, smoothing surface and deep wrinkles (nasolabial, marionette, glabellar), as well as the filling of various types of scars, contouring and lip-plumping and filling in fine lines around the mouth. They help to achieve a sustainable effect of rejuvenation without surgery and laser treatment. The main advantage of dermal fillers is the high rate of effect development, the result is noticeable immediately after the procedure. The basic substance used in dermal fillers - is hyaluronic acid, which is а highly effective and safe product. Stabilized hyaluronic acid of non-animal origin is responsible for skin hydration and toning. It is a powerful natural moisturizing agent contained in the human body, the amount of which decreases over time, which is why the skin becomes drier, thinner and wrinkles start appearing. Hyaluronic acid has an important role in the transfer of nutrients and regulates the skin water balance. It is characterized by a high purity and biocompatibility. HA (hyaluronic acid) retains water, weighing nearly a thousand times larger than its own, and, thus, creates volume and density, maintains optimal moisture balance, improves elasticity, and slows down the aging process. Due to ultra-modern hyaluronic acid gel manufacturing technology, dermal fillers are very easily and quickly injected under the skin, and after the end of the injection process, return the original viscosity. The duration of the effectivity period of the gel, and its stability in tissues increases significantly. Correction procedures using dermal fillers do not require a lot of time for injection and recovery, results appear immediately after the injection and look natural. At average, the treatment takes about 20-30 minutes. Sometimes a necessity of light additional corrections might appear 2 weeks after injection of the filler to achieve the optimal result. The duration of the effect after injection depends on the type of the skin and patient's lifestyle, but at average, it is maintained for up to 4-18 months. The risk of side effects is minimal, but sometimes you may experience some effects, such as swelling, pain, sensitivity, discoloration, allergic reactions, bruising, formation of tubercles, numbness and temporary erythema. Due to the minimum recovery period after injection, patients can immediately return to work and normal activities immediately after treatment. It should be noted that during the first day the patient should avoid excessive exposure to sun and heat or excessive physical activity. The following companies are considered as leading among the manufacturers of dermal fillers: Belotero Merz, Galderma, Filorga, Glytone Pierre Fabre, Allergan, Sinclair, Radiesse Merz Pharma, Vivacy, Teoxane and Croma.